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1.
Indian J Cancer ; 2023 Jun; 60(2): 242-244
Article | IMSEAR | ID: sea-221789

ABSTRACT

Mature cystic teratoma of the ovary is the most common type of germ cell tumor. It constitutes approximately 20% of all ovarian neoplasms. As a rare occurrence, however, several types of benign and malignant tumours developing secondarily in dermoid cysts have been reported. Those of central nervous origin are almost exclusively gliomas of astrocytic, ependymal or oligodendroglial lineage. Choroid plexus tumors are unusual intracranial tumors which comprised of only 0.4?0.6% of all brain tumors. These are neuroectodermal in origin and similar in structure to a normal choroid plexus in the form of multiple papillary fronds mounted on a well vascularized connective tissue stroma. The present case report highlights the presence of a choroid plexus tumor in a mature cystic teratoma of the ovary in a 27?year?old woman who came for safe confinement and cesarean section.

2.
Article | IMSEAR | ID: sea-218660

ABSTRACT

Since the liberalization of trade regulations, Foreign Direct Investment (FDI) has played a crucial role in the expansion of Indian economy, both at the macro and sector levels. The connection between FDI and economic expansion is a debatable subject worldwide. The volume of inflow varies due to a variety of regional, national, and global factors that affect investment choices. Critical policy changes and proactive decision-making demonstrated the government's exceptional resilience, which even helped to mitigate the pandemic's harm. The potential impact of FDI on important macroeconomic indicators is examined in this research paper. In order to analyze the trend of the economic route of future, the study shows the sectoral division of FDI influx. Understanding the divides and patterns helped to provide insight on how the economy was evolving. Changes to regimes are still being made by policymakers in an effort to attract FDI

3.
Article | IMSEAR | ID: sea-206840

ABSTRACT

Background: Mifepristone and Dinoprostone are used in inducing labour in pregnancy by acting as cervical ripening drugs. A randomized case control study to evaluate the efficacy, safety and fetomaternal outcome of induction of labour with oral Mifepristone and intracervical Dinoprostone gel was done.Methods: About 300 patients were included after taking informed consent. 150 patients were placed in each group A and B. In group A patients received 200 mg oral Mifepristone tablet and in group B 0.5 mg Dinoprostone gel was given intracervically and 2nd dose was repeated after 6 hours later if adequate uterine contractions were not achieved. A detailed analysis was carried out in both groups regarding efficacy and safety of drugs in terms of necessity of augmentation of labour with oxytocin, induction to delivery interval, fetal outcome in terms of NICU admission.Results: 59.33% cases in Mifepristone group and 72% case in Dinoprostone group required augmentation with oxytocin. Mean induction delivery interval in Mifepristone group in primigravida was 17.998±1.128 hrs and mean induction delievery interval in multigravida was 11.648±1.112 hours. 88% cases in mifipristone group and 80% cases in Dinoprostone group delivered vaginally. NICU admission was 1.33% in Mifepristone group and 2.66% in PGE2 gel group.Conclusions: Mifepristone when compared with intracervical Dinoprostone gel, acts as a better cervical ripening agent and requires lesser need for Oxytocin augmentation. Though, mean induction delivery interval was more with Mifepistone, the incidence of successful vaginal delivery was higher as compared to Dinoprostone.

4.
Article | IMSEAR | ID: sea-190826

ABSTRACT

Caroli’s disease and Caroli’s syndrome are rare congenital disorders. Caroli’s disease is characterized by multiple sequential cystic or saccular dilatations of the large intrahepatic biliary ducts while Caroli’s syndrome has small bile duct involvement and congenital hepatic fibrosis. The incidence of Caroli’s disease is as low as 1/1,000,000 people. The average age of presentation is early adolescence. Magnetic resonance cholangiopancreatography is a most valuable investigation in diagnosis. Here, we report the case of Caroli’s Type II without renal involvement as late as 6 years of age with severe portal hypertension and hypersplenism. The child had no history of jaundice or recurrent abdominal pain in the past.

5.
Article | IMSEAR | ID: sea-190734

ABSTRACT

Bluish discoloration of the skin and mucous membrane is known as cyanosis which is a clinical sign that occurs in many diseases. The causes of central cyanosis are cardiac shunts causing mixing of oxygenated and deoxygenated blood, lung diseases with ventilation-perfusion mismatch, polycythemia, and methemoglobinemia. Methemoglobin is the oxidized form of hemoglobin, which does not bind oxygen and increases the affinity of oxygen for the partially oxidized portion of hemoglobin. Methemoglobinemia may be congenital or acquired (usually drug induced). Congenital methemoglobinemia is a very rarely reported disease that is caused by a deficiency of nicotinamide adenine dinucleotide phosphate-cytochrome b5 reductase enzyme deficiency or by an abnormal hemoglobin called hemoglobin H. Acquired methemoglobinemia is caused by drugs, namely the sulfonamide group and local anesthetics such as benzocaine and prilocaine. Here, we present the case of a 4-year-old girl who presented with complaints of bluishness of the fingers and lips without any other associated symptoms and later on diagnosed as congenital methemoglobinemia.

6.
Article | IMSEAR | ID: sea-206409

ABSTRACT

Background: In India, many couples complete their families by the age of 25 to 30 years and opt for tubal sterilization as a method of family planning in spite of availability of other spacing methods. Due to unforeseen circumstances, 10 % of them regret their decision and about 1% want to restore their fertility due to various reasons like loss of only child, loss of male child, desire to have more children, loss of children in natural calamities, remarriage and other socioeconomic factors. The objective of the present study was to analyze various factors which are involved in pregnancy rate in tubal recanalization.Methods: 31 women undergoing microsurgical tubal recanalization by mini laparotomy in RRMCH, Bengaluru during a study period of 2 year from 2014 -2016 were followed up for a period of 2 years by telephonic conversation.Results: An overall 67.7 % pregnancy rate was achieved with microsurgery technique.Conclusions: The important factors determining the success of operation were age of the patient, method of previous ligation and the remaining length of tube after recanalization. The microsurgical technique should be available at specialized centres to improve the success of family planning services and also this could be the hope for hopeless.

7.
Article | IMSEAR | ID: sea-186112

ABSTRACT

Background: Eating patterns differ vastly among young adult females due to their body image concern and this consequently affects their BMI status. In most cases the subjects choose to skip meals, change their eating pattern, switch on to exercise so as to lose weight to gain appreciable body image. But it is also seen that in the way to have perfect body image, these subjects tend to have unhealthy food habits that affect their BMI, i.e., either they become underweight or overweight, and it results in malnourishment. The present paper reviews association of eating patterns and body image perception among young adult females and the effect of this association on their BMI. Methodology: In depth literature review was carried out using available search engines such as PubMed, Cochrane Library, Science Direct etc, for published original articles, government reports with specific reference to young adult females were collected. Results: A total of 10 original articles and 3 systematic review articles were included regarding this paper. All the 10 original articles had study subjects belonging to urban background and majority included medical students. A high prevalence of malnourishment was seen among subjects and majority of them were dissatisfied with their body image. Conclusion: This review article focused on the young adult female groups which may be useful for future studies because the body image perception and changing eating patterns are the major issues in the young adult females. Through this review article, various aspects have been revealed that would lead to significant step towards the improvement in the eating patterns of young adult females.

8.
Article | IMSEAR | ID: sea-186133

ABSTRACT

Food taboos are commonly found among around all societies of the world. In every society, culture and beliefs influence the women eating patterns during pregnancy. In Indian society, most food practices and beliefs have emerged from deeply rooted traditions and customs of particular geographical area or culture. Objectives: The objectives of the present study were- 1. To study the prevalence of food taboos and social beliefs among pregnant women. 2. To find out the avoided certain food and reason behind it during the pregnancy. 3. To study the association between the demographic characteristic of pregnant women and food taboos. Methods & Materials: Participants of the study were pregnant 105 women aged 18 to 35 years of Harahua Primary Health Centre, in Varanasi District. The cross-sectional study design was used to obtain the objective of the study. The finding of the study revealed that most of the pregnant women (70.47%) use to avoid some foods during pregnancy. Papaya was the most common food, which was avoided by the pregnant women, and reasons for not consuming the papaya, is it cause were abortion and it is a hot food. The findings of the present study also revealed no association between food taboos and pregnant women demographic characteristics such as age, category, type of family, educational status, socio-economic status, number of pregnancy etc. It means in every type of family, educated women, as well as of high socio-economic backgrounds women use to belief on food taboos.

9.
Article in English | IMSEAR | ID: sea-183103

ABSTRACT

Achondroplasia is a rare disorder occurring in 1 in 15,000 to 1 in 40,000 live births. However, it is the commonest disorder among more than 100 different types of dwarfism. It is inherited as an autosomal dominant trait but most cases (80%) are due to mutations of fibroblast growth factor receptor 3 (FGFR3). These individuals have normal mental and sexual development and life-span may also be normal. However, problems such as pre-eclampsia, polyhydramnios, respiratory compromise, contracted pelvis necessitating lower-segment cesarean section, prematurity and fetal wastage, etc., have been reported. General anesthesia is preferred to regional anesthesia because of spinal abnormalities. The aim of this report is to describe the surgical management of these patients discussing the surgical consideration and emphasizing the difficulties encountered. Such a patient is considered high-risk in terms of anesthesia and obstetric outcome. A case of achondroplasia with pregnancy is reported. A 28-year-old achondroplastic parturient underwent cesarean section under general anesthesia for contracted pelvis. We did not encounter problems related to cesarean section. The most important point is the careful preoperative assessment. Anesthesia plan should be specified to individual basis.

10.
Article in English | IMSEAR | ID: sea-182610

ABSTRACT

Objective: The objective of the study was to evaluate the efficacy of bedside test kits (Actim partus kit) based on detection of phosphorylated insulin-like growth factor binding protein-1(PIGFBP-1) in cervical secretions in predicting preterm delivery. Material and methods: Patients presenting with symptoms of preterm labor between 28 and 36 weeks of gestation were recruited. PIGFBP-1 bedside tests (Actim partus test) were performed. Managing obstetricians and patients were blinded to the PIGFBP-1 results. Tocolysis and steroid therapy were administered to all the recruited patients. Outcome data were collected after delivery. Results: Fifty patients were recruited into the study, the median [± standard deviation [SD] gestational age at delivery was 34.12 weeks (± 2.1 weeks) and 37.14 weeks (± 2.8 weeks), patient testing positive and negative for Actim partus test, respectively. A positive result was associated with significantly reduced admission-to-delivery interval. The median admission-to-delivery interval was 3.25 days in the group with positive PIGFBP-1 results while 6.97 days with a PIGFBP-1 result (p < 0.001). Sensitivity, specificity, positive predictive value and negative predictive value of Actim partus test is 72.22%, 90.6% 81.25% and 85.29%, respectively. Conclusion: Actim partus (IGFBP-1) tests are effective adjuvant bedside test kits for the prediction of preterm delivery in patients presenting with signs or symptoms of preterm labor. High negative predictive values have great value in avoiding unnecessary interventions.

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